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@article{188864,
        author = {Shivraj M. Divthankar and Vinayaksing S. Suryavanshi and Shital R. Dukare and Rohini G. Gaikwad},
        title = {Pharmacovigilance of Nephrotoxic Herbal Medicine Used World wide},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {3856-3864},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=188864},
        abstract = {Introduction Around the world, the usage of herbal remedies is expanding. Particularly in individuals with long-term conditions like kidney illness, where a significant incidence has been found in many studies. However, there are worries regarding the potential negative consequences of herbal remedies. The relationship between the usage of herbs and renal illness has been amply demonstrated by examples from the literature. The necessity to keep an eye on the safety of herbal remedies has grown as their use has increased. Therefore, the World Health Organisation (WHO) advised using natural treatments in the country's current pharmacovigilance programmes. Phytovigilance, also known as pharmacovigilance of medicinal plants, included weighing the advantages and disadvantages of phytotherapy. Protecting patients from herbal harm is the ultimate goal.
Creating trustworthy data on the safety of herbal remedies is crucial.  Phytovigilance is also required by law when it comes to interactions between multiple related plants and hazards of toxicity (acute or chronic) or drug interactions (pharmacokinetic or pharmacodynamics).  There are a number of problems with the naming, perception, acquisition, and application of herbal medications.  The WHO released guidelines on pharmacovigilance of herbal medicines on a global scale.  However, in most African nations, it is still a relatively young activity.  With the exception of Morocco, where a phytotherapy pharmacovigilance program was established in 2000.  Including the development of Phytotoxic and Botanicals.  Understanding, identifying, and keeping an eye on adverse reactions through pharmacovigilance of herbal medicine activities is necessary in this case. There are a number of problems with the naming, perception, acquisition, and application of herbal medications.  The WHO released guidelines on pharmacovigilance of herbal medicines on a global scale.  However, in most African nations, it is still a relatively young activity.  With the exception of Morocco, where a phytotherapy pharmacovigilance program was established in 2000.  Including the development of Phytotoxic and Botanicals.  Understanding, identifying, and keeping an eye on adverse reactions through pharmacovigilance of herbal medicine activities is necessary in this case.  Systematic study was done on Pub Med, Science Direct, and Scopus to demonstrate the adverse consequences of using herbal medications on the kidneys and the present global requirement to maintain Phytovigilance. Additionally, a few readily available databases on Phytovigilance or pharmacovigilance of herbal medication were explored.  Aristolochic acid nephropathy, which is linked to the abuse of some traditional Chinese herbal remedies, is the most well-known herb-induced kidney damage.  There is a dearth of information regarding the nephrotoxicity of European plant species.  Here, we critically examine important facts about the nephrotoxicity of a number of plants utilised in European phytotherapy, such as Aloe, Euphorbia paralias, Glycyrrhiza glabra, and Artemisia herba-alba.  There is discussion of the causes and risk factors for herbal intoxications.  Improving pharmacovigilance of herbal medicine, particularly in patients with chronic renal disease, is the main goal of this review.},
        keywords = {Herbal products, Nephrotoxicity, pharmacovigilance.},
        month = {December},
        }