DEVELOPMENT OF ANALYTICAL METHOD FOR THE DETERMINATION OF PIRACETAM IN BULK DRUG AND ITS PHARMACEUTICAL FORMULATION

  • Unique Paper ID: 188920
  • Volume: 12
  • Issue: 7
  • PageNo: 3930-3936
  • Abstract:
  • This study presents the development and validation of a simple, rapid, and economic UV-visible spectrophotometric method for the estimation of Piracetam in bulk and pharmaceutical formulation. Using Systronics 2202TS spectrophotometer, the method employed a diluent mixture of Methanol and distilled water (40:60) to ensure solubility and stability. The maximum absorbance was observed at 205 nm. The method demonstrated linearity following Beer’s Law in the concentration range of 5-25 µg/ml. Validation parameters confirmed high reliability: the assay of Sancetam 800 mg tablets indicated 98.84% purity, while recovery studies yielded a value of 102%. Precision was established with a Relative Standard Deviation of 0.38%, indicating the method is highly reproducible and suitable for routine quality control analysis.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{188920,
        author = {Dr.  R. Xavier Arulappa and M. Jerubin Welsingh and Akash. A and Anjali. B and Aswani B.R and Mannya. M and Navya. S Kumar and Prasobh G. R},
        title = {DEVELOPMENT OF ANALYTICAL METHOD FOR THE DETERMINATION OF PIRACETAM IN BULK DRUG AND ITS PHARMACEUTICAL FORMULATION},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {3930-3936},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=188920},
        abstract = {This study presents the development and validation of a simple, rapid, and economic UV-visible spectrophotometric method for the estimation of Piracetam in bulk and pharmaceutical formulation. Using Systronics 2202TS spectrophotometer, the method employed a diluent mixture of Methanol and distilled water (40:60) to ensure solubility and stability. The maximum absorbance was observed at 205 nm. The method demonstrated linearity following Beer’s Law in the concentration range of 5-25 µg/ml. Validation parameters confirmed high reliability: the assay of Sancetam 800 mg tablets indicated 98.84% purity, while recovery studies yielded a value of 102%. Precision was established with a Relative Standard Deviation of 0.38%, indicating the method is highly reproducible and suitable for routine quality control analysis.},
        keywords = {Analytical Method Validation, Beer’s Lambert Law, Linearity, Methanol, Piracetam, Recovery Studies, UV-Visible Spectrophotometry.},
        month = {December},
        }

Cite This Article

Arulappa, D. . R. X., & Welsingh, M. J., & A, A., & B, A., & B.R, A., & M, M., & Kumar, N. S., & R, P. G. (2025). DEVELOPMENT OF ANALYTICAL METHOD FOR THE DETERMINATION OF PIRACETAM IN BULK DRUG AND ITS PHARMACEUTICAL FORMULATION. International Journal of Innovative Research in Technology (IJIRT), 12(7), 3930–3936.

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