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@article{189278,
        author = {Kartik B. Sakhare and Madhuri A. Theng},
        title = {ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF BREVARACETAM BY RP-HPLC METHOD},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {5453-5459},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189278},
        abstract = {The analytical method was developed and validated for estimation of Brivaracetam in bulk and formulation by Reverse Phase High performance liquid chromatography. The separation was carried out on Luna C8 (150 × 4.6mm, 5µm) column. The mobile phase consists of ACN: Water at flow rate 1 ml/min at 208nm. The column temperature was adjusted at 30°C with injection volume 20µl. The retention time of Brivaracetam was 3.1 min. The linearity of the calibration curve was linear over the concentration range 10-50 µg/ml. The developed method was validated according to the International Council for Harmonization (ICH) Guidelines. The developed method was easy, rapid, linear, precise, accurate and consistent. So, the method can be successfully applied for the routine analysis of Brivaracetam in pharmaceutical formulation.},
        keywords = {RP-HPLC, Method Validation, Estimation, Chromatogram.},
        month = {December},
        }