Nanogels as an advanced drug delivery system

  • Unique Paper ID: 189279
  • Volume: 12
  • Issue: 7
  • PageNo: 6101-6114
  • Abstract:
  • Nanogels have really caught people’s attention lately as a smart, flexible way to deliver drugs. Thanks to their tiny, sponge-like structure, they can soak up a lot of water or biological fluids and still hold their shape. That’s a big deal because it lets nanogels carry all kinds of therapies small-molecule drugs, proteins, peptides, even genes and vaccines. Unlike older drug delivery tricks, nanogels bring a lot to the table: they keep drugs stable, pack in a lot of medicine, release it in a controlled way, and can even zero in on specific tissues or cells. You can tweak all sorts of things about nanogels their size, charge, porosity, how much they swell to suit whatever the treatment calls for. And it gets better: scientists have figured out how to make nanogels that respond to things like pH, temperature, enzymes, or redox changes. That means you can trigger drug release exactly when and where you want it. This is a game-changer for tough diseases like cancer, inflammatory problems, or neurological issues, where you need to hit the right spot without causing a bunch of side effects elsewhere. In this review, you’ll get a full look at nanogels as a drug delivery system what they are, what they’re made of, how they’re classified, how people make them, how they load up drugs, and how the drugs get released. We’ll also dig into the latest applications, the benefits and drawbacks, what regulators are saying, and where the field is heading. Bottom line: nanogels are shaping up to be a powerful tool that could make treatments work better and actually help patients more in the future of medicine.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{189279,
        author = {Gaurav Bhimrao Gacche and Ms. Pradnya M. Kshirsagar},
        title = {Nanogels as an advanced drug delivery system},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {6101-6114},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189279},
        abstract = {Nanogels have really caught people’s attention lately as a smart, flexible way to deliver drugs. Thanks to their tiny, sponge-like structure, they can soak up a lot of water or biological fluids and still hold their shape. That’s a big deal because it lets nanogels carry all kinds of therapies small-molecule drugs, proteins, peptides, even genes and vaccines. Unlike older drug delivery tricks, nanogels bring a lot to the table: they keep drugs stable, pack in a lot of medicine, release it in a controlled way, and can even zero in on specific tissues or cells. You can tweak all sorts of things about nanogels their size, charge, porosity, how much they swell to suit whatever the treatment calls for. And it gets better: scientists have figured out how to make nanogels that respond to things like pH, temperature, enzymes, or redox changes. That means you can trigger drug release exactly when and where you want it. This is a game-changer for tough diseases like cancer, inflammatory problems, or neurological issues, where you need to hit the right spot without causing a bunch of side effects elsewhere. In this review, you’ll get a full look at nanogels as a drug delivery system what they are, what they’re made of, how they’re classified, how people make them, how they load up drugs, and how the drugs get released. We’ll also dig into the latest applications, the benefits and drawbacks, what regulators are saying, and where the field is heading. Bottom line: nanogels are shaping up to be a powerful tool that could make treatments work better and actually help patients more in the future of medicine.},
        keywords = {Advanced drug delivery system, Polymeric nanocarriers, Stimuli-responsive nanogels, Controlled drug release, Targeted drug delivery, Hydrogel nanoparticles, Pharmaceutical nanotechnology.},
        month = {December},
        }

Cite This Article

Gacche, G. B., & Kshirsagar, M. P. M. (2025). Nanogels as an advanced drug delivery system. International Journal of Innovative Research in Technology (IJIRT), 12(7), 6101–6114.

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