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@article{189309,
        author = {Amit Vishwakarma and Dr. Poonam Maurya},
        title = {Nanosponge in Current Treatment of Schizophrenia},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {5882-5887},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189309},
        abstract = {Clozapine is frequently necessary for cases of schizophrenia, a crippling mental illness, that do not respond to treatment. Poor oral bioavailability and notable dose-dependent side effects, however, limit its therapeutic efficacy. To get over these restrictions, the nose-to-brain route offers a viable substitute. This review article gives a clear summary of why and how a new drug delivery system was created and tested. The system uses a special tiny sponge filled with clozapine, placed inside a sticky nasal gel for easy delivery through the nose. The benefits of nasal drug delivery, the synergistic potential of their combination, and the existing literature on nano sponge technology are all thoroughly examined. This review focuses on future research directions to address the unmet requirements of patients with schizophrenia by highlighting important formulation strategies, characterisation techniques, and the possible clinical benefit of this novel strategy.},
        keywords = {},
        month = {December},
        }