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@article{189447,
        author = {KOLASANI VENKATA RAMAIAH and KAANDURI SESHA SITA GODHA MOHANA and MULE VENKATACHENNAKESAVAREDDY and , VENKATAPRASANNAKUMAR.GOLI and MANGALAPUDI RAMI REDDY},
        title = {The Spread of Scrub Typhus in Andhra Pradesh: Epidemiology, Clinical Trends, and Public Health Responses},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {6407-6420},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189447},
        abstract = {Scrub typhus is a re-emerging vector-borne zoonotic disease caused by Orientia tsutsugamushi and transmitted through the bite of infected chigger mites. In recent years, Andhra Pradesh has reported a notable rise in scrub typhus cases, particularly during the post-monsoon period, making it a significant contributor to acute undifferentiated febrile illness in the region. This article reviews the epidemiology, clinical manifestations, pathophysiology, and public health responses related to scrub typhus, with a specific focus on Andhra Pradesh. The disease presents with a wide clinical spectrum, ranging from mild fever and headache to severe complications such as acute respiratory distress syndrome, renal failure, myocarditis, and meningoencephalitis if diagnosis and treatment are delayed. Environmental factors, occupational exposure, and seasonal vector dynamics play a critical role in disease transmission. Strengthened surveillance, improved diagnostic capacity, early antibiotic therapy with doxycycline or azithromycin, and enhanced public awareness campaigns have significantly contributed to better disease control. Recent initiatives by the Andhra Pradesh government, including genome sequencing, task force formation, and stockpiling of essential medicines, demonstrate a proactive public health approach. Continued surveillance, clinician awareness, and integrated vector control strategies are essential to reduce morbidity, mortality, and future outbreaks of scrub typhus.},
        keywords = {Scrub typhus, Orientia tsutsugamushi, Chigger mite, Acute febrile illness, Epidemiology, Andhra Pradesh, Public health response},
        month = {December},
        }