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@article{189491,
        author = {Swapnali Kondake and Gayathri Muley},
        title = {ANIMAL MODELS FOR EVALUATION OF ANTIDEPRESSANT ACTIVITY: A REVIEW},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {6574-6576},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189491},
        abstract = {Depression is a common and serious psychiatric disorder that affects mood, behavior, and overall quality of life. It is one of the leading causes of disability worldwide and poses a major public health challenge. Preclinical evaluation using animal models plays a crucial role in understanding the neurobiological basis of depression and in screening potential antidepressant drugs before clinical use. Since depression cannot be fully reproduced in animals, different experimental models are used to mimic specific behavioral and neurochemical aspects of the disorder. This review discusses commonly used animal models for the evaluation of antidepressant activity, including behavioral despair models and stress-based models. Emphasis is given to their methodology, advantages, limitations, and relevance to human depression.},
        keywords = {Depression, Antidepressant drugs, Animal models, Forced swim test, Tail suspension test},
        month = {December},
        }