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@article{189646,
        author = {Shaikh Muskan Sultan and Shinde Vaishnavi Dattatray and Dr. Dharashive Vishweshwar M. and Bhise Rutuja Rajaram},
        title = {Herbal Transdermal Patch: Formulation and Evaluation},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {7045-7056},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189646},
        abstract = {Herbal transdermal patches are an emerging promising niche for the controlled release of bioactive phytochemicals in an unconventional, patient-centric transdermal method that avoids bioavailability restrictions in oral delivery by promoting transdermal permeability. The herbal compactions in the transdermal patches were developed using the solvent evaporation method by incorporating lipophilic extracts of neem, gingerol, menthol, capsaicin, curcumin from turmeric and Centella asiatica in suitable concentrations of HPMC, PVA, EC, and PVP in glycerin plasticizers (20% v/v concentrations), DMSO, and an ethanol and water solvent mixture (1:1proportions), which were cast and evaporated in Petri dishes. Comprehensively rigorous evaluations included uniformity testing (weight, thickness, and uniformity of Herbal contents by UV techniques at 276nm wavelengths), mechanical testing (folding endurance, tensile strength, and elongations at break), and also comprehensive physicochemical characterizations such as moisture content and absorption capacity, surface pH of 5-6, release characteristics in fluid media, and also ex vivo skin permeability using the Franz cell system utilizing pigskins and adhesion force/tensile methods using tack and peel tests by imaging .},
        keywords = {bioactive phytochemicals, biodegradable carrier agents, comprehensive physicochemical analysis, controlled release characteristics, ex vivo permeability studies, Herbal drug delivery, matrix polymers, Natural Herbal Patches, permeability-enhancing agents, solvent evaporation method},
        month = {December},
        }