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@article{189694,
        author = {Mrunal M. Karanjkar and Sakshi S. Suryavanshi and Priyanka D. Hankare and Tejas A. Nikam},
        title = {A SUBJECT REVIEW ON SYNTHETIC CHEMISTRY},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {7361-7379},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189694},
        abstract = {Modern pharmaceutical innovation is supported by synthetic chemistry, which makes it possible to find, create, and produce life-saving medications and materials on a massive scale.  The development of synthetic techniques and their revolutionary impact on drug discovery, industrial processes, and sustainable practices are highlighted in this overview.  Traditional organic synthesis has given way to more sophisticated methods that combine automation, artificial intelligence, and reaction miniaturization. Technological advancements including flow chemistry, microreactors, biocatalysis, photoredox and electrochemical synthesis, and chemoenzymatic approaches have increased the available chemical space while enhancing scalability, efficiency, and selectivity.  Furthermore, late-stage functionalization and transition-metal-catalyzed C–H activation offer strong instruments for enhancing therapeutic candidates and diversifying molecular scaffolds.
Green chemistry concepts have changed synthesis goals, placing more emphasis on waste reduction, cleaner solvents, atom economy, and renewable feedstocks, in addition to technological advancements.  The emergence of green solvents, such as polyethylene glycol, water, supercritical carbon dioxide, and ionic liquids, shows how eco-friendly substitutes can be included into industrial operations.  Today, metrics like the E-factor and atom economy are used to evaluate synthetic sustainability, bringing chemical innovation into line with global resource and climate issues.
All things considered, synthetic chemistry is undergoing a paradigm change as sustainability and innovation come together.Drug discovery could be accelerated while maintaining tractable synthetic routes thanks to emerging AI-driven design, automation of the design-make-test cycle, and incorporation of generative models into synthesis planning.  The field is moving toward a future that strikes a balance between effectiveness, innovation, and environmental responsibility by fusing contemporary techniques with the ideas of green chemistry, reinforcing synthetic chemistry as a fundamental component of science and medicine.},
        keywords = {Artificial Intelligence, Biocatalysis, Green Chemistry, Photoredox & Electrochemical Synthesis,  Synthetic chemistry.},
        month = {December},
        }