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@article{189824,
        author = {V.Geetha},
        title = {Green Chemistry Approaches in Drug Synthesis: Towards Sustainable Medicinal Chemistry},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {1498-1508},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189824},
        abstract = {Green chemistry has emerged as a vital framework in the transformation of drug synthesis, aiming to align pharmaceutical development with the principles of sustainability. Conventional synthetic processes often involve the use of hazardous reagents, excessive solvent use, and energy-intensive conditions, which contribute to environmental degradation and industrial inefficiency. In contrast, green chemistry seeks to minimize waste, utilize renewable materials, and employ safer reaction conditions without compromising efficacy or productivity. This paper reviews various green chemistry methodologies, including biocatalysis, flow chemistry, solvent-free reactions, and the application of environmentally benign catalysts and solvents. Through selected case studies, it illustrates how these approaches can yield improved reaction efficiency, reduced environmental impact, and greater process safety. The paper concludes with an analysis of existing barriers and future directions for integrating green chemistry into mainstream pharmaceutical synthesis.},
        keywords = {Green chemistry, sustainable synthesis, pharmaceutical development, biocatalysis, flow chemistry, solvent-free reactions, eco-friendly solvents, catalysis.},
        month = {January},
        }