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@article{189932,
        author = {Priya Kumar and K. Saravanan and Vikas saxena},
        title = {Chemical Characterization and Therapeutic Evaluation of Condensed Cinnolo-Isothiazole Derivatives},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {1829-1837},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189932},
        abstract = {This study reports the synthesis of a series of substituted cinnoline derivatives condensed with an isothiazole moiety, yielding a new series of substituted cinnoline–isothiazole compounds (13a–13j). All synthesized compounds were obtained in good yields and high purity and were evaluated for their antibacterial and antifungal activities. The methodology, experimental procedures, and biological evaluation of ten different substituted cinnoline–isothiazole derivatives are described through a multistep reaction scheme. Structural characterization of the synthesized compounds was carried out using spectroscopic techniques, including IR, 1H NMR, and mass spectrometry. Biological evaluation revealed that several compounds exhibited promising antimicrobial activity. In particular, chloro-substituted derivatives (13DSDg) afforded the highest synthetic yield, while compounds 13DSDc, 13DSDd, 13DSDf, and 13DSDi showed hit compounds against antibacterial activity and antifungal activity.},
        keywords = {Cinnoline–isothiazole derivatives, Antibacterial, and Anti-fungal},
        month = {January},
        }