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@article{190309,
        author = {Jitendra Kumar Dwivedi and Alok Kumar Singh and Kapil Kumar Yadav and Monika Singh and Gyan Prakash Srivastava and Anshuman Gupta and Prashant Kumar and Amit Jaiswal},
        title = {Potential Activity of fungal Endophyte of Lasiodiplodia theobromae isolated from Crateva religiosa as a good source of Antibacterial and Antifungal Compounds},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {3731-3739},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190309},
        abstract = {Endophytic microorganisms reside within specific tissues of host plants without causing any apparent symptoms. Fungal endophytes are known to produce a wide range of bioactive compounds with significant therapeutic potential. Crateva religiosa is a sacred and traditionally important medicinal plant that has been widely used in various medical systems to treat numerous ailments. This plant serves as a rich reservoir of endophytes capable of synthesizing diverse pharmacologically active metabolites.
The present study focuses on the isolation of the fungal endophyte Lasiodiplodia theobromae from different tissues of C. religiosa. The crude extracts obtained from this endophytic fungus exhibit antibacterial activity against both Gram-positive and Gram-negative bacteria. Thin Layer Chromatography (TLC) and Gas Chromatography–Mass Spectrometry (GC–MS) were employed to characterize the bioactive compounds produced by the endophyte.
Phytochemical analysis confirmed the presence of alkaloids, flavonoids, tannins, terpenoids, steroids, carbohydrates, and amino acids in the fungal extract. GC–MS profiling of the Lasiodiplodia extract revealed several bioactive constituents of medicinal relevance.},
        keywords = {Crateva religiosa, Endophytes, GC–MS, Lasiodiplodia theobromae, Secondary metabolites},
        month = {January},
        }