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@article{190462,
        author = {Iqra Husain Raini and Dr. Shobhit Prakash Shrivastava},
        title = {Phytochemical screening and Anti-Arthritic activity of Polemonium Reptans Leaves Ethanolic extract on Albino Wistar Rats},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {3274-3280},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190462},
        abstract = {Arthritis occurs as a defensive response, which includes physiological adaptations to limit tissue damage and remove pathogenic infections. The ethanolic leaf extract of Polemonium reptans was assessed for its in vivo anti-arthritic activity. Arthritis is an inflammatory disease, and many plant-derived anti-inflammatory compounds have shown promise as anti-arthritic agents. The presence of flavonoids and triterpenoids in P. reptans suggests the potential for such effects, as these compound classes have demonstrated anti-arthritic properties in other medicinal plants through mechanisms such as inhibiting inflammatory mediators and stabilizing cell membranes. Qualitative preliminary phytochemical screening revealed that the leaves of P. reptans, as extracted using ethanol, contained alkaloids, tannins, flavonoids, glycosides, phenolic compounds, terpenoids, and volatile oils. The anti-arthritis efficacy of the ethanolic extract was evaluated against formaldehyde-induced rat paw edema at different doses (200 and 400 mg/kg body weight) administered orally, while diclofenac (13.5 mg/kg) served as the standard. Changes in the paw volume of rats were measured using a mercury plethysmometer.},
        keywords = {Index Terms—Arthritis, anti-arthritic agents, medicinal plants, phytochemicals, Wistar rats},
        month = {January},
        }