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@article{188740,
author = {DIVYA RAO and Dr. Shobhit Prakash Shrivastava},
title = {Preparation, Phytochemical Analysis and Wound-Healing Screening of a Polyherbal Formulation in Albino Wistar Rats},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {12},
number = {7},
pages = {3192-3200},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=188740},
abstract = {Wound management is a clinical problem, which has raised the interest in plant-based interventions. Polyherbal preparations - mixtures of extracts of medicinal plants - have become the focus of interest due to their synergy in wound healing [1][2]. This review summarizes the preparation procedure of a polyherbal wound-healing formulation, its phytochemical components and efficacy of such preparations in an albino Wistar rat wound model. Polyherbal remedies take advantage of several bioactive molecules to speed up the healing process by regulating inflammation, stimulating collagen synthesis, fighting microbial infection, and improving tissue regeneration [3][4]. Recent experiments on rats show that ointments or gels of plant extracts (i.e., Curcuma longa, Aloe vera, Centella asiatica, Azadirachta indica) cause a significant improvement in wound contraction, healing time, and tensile strength of repair tissue as compared to controls [5][6]. The phytochemical studies indicate that these preparations contain high levels of flavonoid, phenolic, tannin and other antioxidants which form the basis of their therapeutic activity [7][8]. In general, polyherbal preparations are a potential biocompatible approach to wound healing, which should be developed in terms of clinical application.},
keywords = {Wound healing, polyherbal formulation, medicinal plants, phytochemicals, Wistar rats},
month = {December},
}
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