Antiviral plants and phytoconstituent emerging in post pandemic era

  • Unique Paper ID: 190497
  • Volume: 12
  • Issue: 8
  • PageNo: 1181-1188
  • Abstract:
  • The international COVID-19 pandemic has escalated the need for novel and effective antiviral treatments from natural sources, as the shortcomings of current synthetic medications, including emerging resistance and unwanted harmful side effects, has become clearer. Medicinal plants have long been acknowledged as rich sources of phytochemicals, such as flavonoids, alkaloids, terpenoids, and phenolic compounds, to name a few, that have been shown to exhibit diverse antiviral activity, with many acting in remarkably resilient ways across various viral families. The bioactive metabolites of medicinal plants have the potential to curtail viral entry, replication, and assembly, as well as simultaneously modulate host immune responses, providing a approach to combating viral infectious agents. Evidence from traditional systems of medicine, as well as modern pharmacological studies, continues to uncover the broad-spectrum potential of plants against viral pathogens including SARS-CoV-2, HIV, hepatitis viruses, and influenza. Clinical and preclinical studies, as well as molecular docking and in silico analysis, provide numerous lines of evidence for the therapeutic potential of plant-derived compounds specifically for their ability to subvert viral pathogenesis. Molecular docking studies and pharmacological studies also provide insights into the mechanisms or ways these bioactive metabolites affinity or interact with viral proteins, providing a rationale for drug development. In addition to this, many of these natural compounds also have fewer side effects compared to conventional antiviral agents, making them potential options for long-term use or in combination with other therapy. A growing body of evidence shows that ethnopharmacology and modern virology may work together to discover plant-derived antiviral agents to combat current and future health threats.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{190497,
        author = {Anuj Sanjay Bagul and Dr.Babita More and Dr.Rupali Tasgaonkar},
        title = {Antiviral plants and phytoconstituent emerging in post pandemic era},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {1181-1188},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190497},
        abstract = {The international COVID-19 pandemic has escalated the need for novel and effective antiviral treatments from natural sources, as the shortcomings of current synthetic medications, including emerging resistance and unwanted harmful side effects, has become clearer. Medicinal plants have long been acknowledged as rich sources of phytochemicals, such as flavonoids, alkaloids, terpenoids, and phenolic compounds, to name a few, that have been shown to exhibit diverse antiviral activity, with many acting in remarkably resilient ways across various viral families. The bioactive metabolites of medicinal plants have the potential to curtail viral entry, replication, and assembly, as well as simultaneously modulate host immune responses, providing a approach to combating viral infectious agents. Evidence from traditional systems of medicine, as well as modern pharmacological studies, continues to uncover the broad-spectrum potential of plants against viral pathogens including SARS-CoV-2, HIV, hepatitis viruses, and influenza. Clinical and preclinical studies, as well as molecular docking and in silico analysis, provide numerous lines of evidence for the therapeutic potential of plant-derived compounds specifically for their ability to subvert viral pathogenesis. Molecular docking studies and pharmacological studies also provide insights into the mechanisms or ways these bioactive metabolites affinity or interact with viral proteins, providing a rationale for drug development. In addition to this, many of these natural compounds also have fewer side effects compared to conventional antiviral agents, making them potential options for long-term use or in combination with other therapy. A growing body of evidence shows that ethnopharmacology and modern virology may work together to discover plant-derived antiviral agents to combat current and future health threats.},
        keywords = {Antiviral medicinal plants Phytoconstituents Phytochemical Herbal Antiviral Plant-derived antivirals, post-pandemic era, COVID-19, Viral infections, Secondary metabolites Flavonoids, Alkaloid Terpenoids, Polyphenols Drug discovery, Alternative and complementary medicine},
        month = {January},
        }

Cite This Article

Bagul, A. S., & More, D., & Tasgaonkar, D. (2026). Antiviral plants and phytoconstituent emerging in post pandemic era. International Journal of Innovative Research in Technology (IJIRT), 12(8), 1181–1188.

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