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@article{190623,
        author = {Kandakatla Tejasri and M. Rakesh},
        title = {ANTIOXIDANT AND ANTIMICROBIAL ACTIVITY STUDY OF CHROMOLAENA ODORATA ROOT EXTRACT},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {2904-2908},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190623},
        abstract = {Oxidative stress, characterized by an imbalance between the production of reactive oxygen species (ROS) and endogenous antioxidant defenses, plays a pivotal role in the pathogenesis of numerous chronic diseases. This condition is significantly exacerbated during microbial infections and can drive the initiation and progression of cancer by damaging essential macromolecules, including DNA, proteins, and lipids. Antioxidants Act as the brakes, stopping the stress from hurting you. The current study has developed to assess the antioxidant and antimicrobial effect of ethanolic and aqueous extract of chromolaena odorata roots. Aqueous, ethanolic, and chloroform extracts were assessed using DPPH radical scavenging, nitric oxide scavenging, Hydroxyl radical scavenging activity, and aqueous and ethanolic extracts are assayed using Disc diffusion and Cup Plate Method against standard antibiotic control sample. All the extracts showed a positive correlation with antioxidant activity, antibacterial sensitivity test revealed that ethanolic extracts of Chromolaena odorata roots at 50%, 20%, 10% and 5% concentrations showed antibacterial activities against Staphylococcus aureus and Bacillus cereus in both Disc diffusion assay and Cup Plate Method. These results demonstrate that the roots of Chromolaena odorata exhibit potent antioxidant and antimicrobial activities, underscoring their potential as a viable natural reservoir for the development of novel antimicrobial therapeutics.},
        keywords = {Chromolaena odorata, Antioxidant activity, Antimicrobial, DPPH assay, nitric oxide scavenging, Hydroxyl radical scavenging activity, Disc diffusion assay},
        month = {January},
        }