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@article{193576,
        author = {Dr Sarika Manohar Desai and Vd Poonam Digambar Shinge},
        title = {Efficacy of Mutravirechaniya Dravyas in Recurrent Urinary Tract Infections: A Comprehensive Review},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {10},
        pages = {1479-1485},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=193576},
        abstract = {Recurrent urinary tract infections (rUTIs) constitute a major public health concern, particularly among women of reproductive age, pregnant individuals, post-menopausal women, diabetic patients, and the elderly. Clinically defined as two or more episodes within six months or three or more episodes within one year, rUTIs are most frequently caused by uropathogenic Escherichia coli, which possess virulence determinants such as fimbrial adhesion molecules, intracellular bacterial community formation, and biofilm production. Despite appropriate antibiotic therapy, recurrence rates remain high due to microbial persistence, reinfection, host immune susceptibility, urinary stasis, and disruption of the genitourinary microbiota. The global rise in antimicrobial resistance further complicates management and underscores the need for preventive and integrative therapeutic strategies. In Ayurveda, recurrent urinary infections correlate with Mutrakricchra, Mutraghata, and Mutravaha Srotodushti, primarily involving vitiation of Pitta and Kapha Doshas with secondary Ama accumulation and impaired Agni. Classical management emphasizes Mutravirechaniya Dravyas a group of herbs that promote diuresis, cleanse urinary channels, pacify inflammation, and restore physiological balance. These botanicals are described to exert Pittashamana, Daha-prashamana, Srotoshodhana, and Rasayana actions, thereby addressing both symptomatology and recurrence tendency. Contemporary pharmacological investigations suggest that several Mutravirechaniya herbs exhibit diuretic, antimicrobial, anti-inflammatory, antioxidant, anti-adhesive, and immunomodulatory properties. Experimental models demonstrate nephroprotective activity and inhibition of bacterial colonization, while preliminary clinical studies indicate symptomatic relief and reduced recurrence frequency when used adjunctively. This review synthesizes classical Ayurvedic descriptions with modern biomedical evidence to critically evaluate the potential role of Mutravirechaniya Dravyas in the management and prevention of recurrent UTIs. Although current evidence is promising, high-quality randomized controlled trials with standardized formulations and microbiological endpoints are required to establish definitive efficacy and clinical guidelines.},
        keywords = {Recurrent UTI, Mutravirechaniya, Mutrakricchra, Biofilm, Antimicrobial Resistance, Ayurveda, Integrative Urology},
        month = {March},
        }