Neuro-Electro-Hormonal Model of Insulin Regulation and Sugar Homeostasis

  • Unique Paper ID: 194257
  • Volume: 12
  • Issue: 10
  • PageNo: 3517-3520
  • Abstract:
  • Conventional endocrinology explains insulin regulation primarily as a biochemical response of the pancreas to blood glucose levels. However, clinical observations reveal significant inter individual variation: some individuals develop severe symptoms at extremely high glucose levels, while others remain largely asymptomatic. This paper proposes the Neuro Electro Hormonal Model of Insulin Regulation and Sugar Homeostasis, in which insulin production, release, and effectiveness are governed not only by pancreatic beta cells, but by a brain pituitary pancreas electro chemical signalling axis. Functional formulae and flowcharts illustrate how a single hormone (insulin) manifests multiple inner functional states and how hormonal imbalance, stress, and neural energy dysregulation contribute to sugar related diseases.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{194257,
        author = {Dr Shishir Mishra and Dr Manoj Prabhakar and Dr Santosh Chuhan},
        title = {Neuro-Electro-Hormonal Model of Insulin Regulation and Sugar Homeostasis},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {10},
        pages = {3517-3520},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=194257},
        abstract = {Conventional endocrinology explains insulin regulation primarily as a biochemical response of the pancreas to blood glucose levels. However, clinical observations reveal significant inter individual variation: some individuals develop severe symptoms at extremely high glucose levels, while others remain largely asymptomatic. This paper proposes the Neuro Electro Hormonal Model of Insulin Regulation and Sugar Homeostasis, in which insulin production, release, and effectiveness are governed not only by pancreatic beta cells, but by a brain pituitary pancreas electro chemical signalling axis. Functional formulae and flowcharts illustrate how a single hormone (insulin) manifests multiple inner functional states and how hormonal imbalance, stress, and neural energy dysregulation contribute to sugar related diseases.},
        keywords = {Neuro Electro Hormonal Model, Insulin, Hormones, Blood Sugar, Brain Pancreas Axis, Electro chemical signalling, Stress, Diabetes, Hormonal diseases},
        month = {March},
        }

Cite This Article

Mishra, D. S., & Prabhakar, D. M., & Chuhan, D. S. (2026). Neuro-Electro-Hormonal Model of Insulin Regulation and Sugar Homeostasis. International Journal of Innovative Research in Technology (IJIRT), 12(10), 3517–3520.

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