Toxic Effects of Chlorpyrifos on Biochemical and Haematological Parameters in Albino Mice (Mus musculus) and the Reversal Potential of Onion (Allium cepa)

  • Unique Paper ID: 196516
  • Volume: 12
  • Issue: 11
  • PageNo: 4393-4400
  • Abstract:
  • People have been using pesticides for days back thousands of years, with early humans using natural chemicals like Sulphur, mercury, and arsenic to tackle pests and guard crops (Pimentel, 2005). In ancient Greece and Rome, extracts of plants like hellebore and tobacco were applied to resist insects. The modern era of pesticides, however, started in the mid, 20th century with the epiphany and large, scale application of synthetic formulas namely dichlorodiphenyltrichloroethane (DDT). DDT earned spotlight amidst World War II when it was successfully used to clash malaria and typhus, but soon issues about its environmental tenacity and bioaccumulation were lifted (Carson, 1962). Rachel Carson’s landmark book Silent Spring agitated worldwide talks and policy changes, leading to stricter regulations and ultimate bans on DDT in numerous countries. Today, pesticides have become a necessary factor in modern agriculture, and through their application, they play a major role in both increasing crop productivity, and precluding post, harvest loss. Subsequently, they also contribute to food security (Cooper & Dobson, 2007). Nevertheless, this substantial reliance has also given birth to a double- edged sword— raising agricultural productivity at the expense of the environment and human health in the long run.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{196516,
        author = {Preeti Kumari and Dr. Pushpalata Dubey},
        title = {Toxic Effects of Chlorpyrifos on Biochemical and Haematological Parameters in Albino Mice (Mus musculus) and the Reversal Potential of Onion (Allium cepa)},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {11},
        pages = {4393-4400},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=196516},
        abstract = {People have been using pesticides for days back thousands of years, with early humans using natural chemicals like Sulphur, mercury, and arsenic to tackle pests and guard crops (Pimentel, 2005). In ancient Greece and Rome, extracts of plants like hellebore and tobacco were applied to resist insects. The modern era of pesticides, however, started in the mid, 20th century with the epiphany and large, scale application of synthetic formulas namely dichlorodiphenyltrichloroethane (DDT). DDT earned spotlight amidst World War II when it was successfully used to clash malaria and typhus, but soon issues about its environmental tenacity and bioaccumulation were lifted (Carson, 1962). Rachel Carson’s landmark book Silent Spring agitated worldwide talks and policy changes, leading to stricter regulations and ultimate bans on DDT in numerous countries. Today, pesticides have become a necessary factor in modern agriculture, and through their application, they play a major role in both increasing crop productivity, and precluding post, harvest loss. Subsequently, they also contribute to food security (Cooper & Dobson, 2007). Nevertheless, this substantial reliance has also given birth to a double- edged sword— raising agricultural productivity at the expense of the environment and human health in the long run.},
        keywords = {Pesticide, Chemical, Synthetic, Policy, Malaria},
        month = {April},
        }

Cite This Article

Kumari, P., & Dubey, D. P. (2026). Toxic Effects of Chlorpyrifos on Biochemical and Haematological Parameters in Albino Mice (Mus musculus) and the Reversal Potential of Onion (Allium cepa). International Journal of Innovative Research in Technology (IJIRT), 12(11), 4393–4400.

Related Articles