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@article{197097,
        author = {MR.S.G.RAMAN and DR.R.SUNDHARARAJAN and Heerani.G and Keerthivasan.P.V and Mohammed Arshath.I and Suhail Ahamed, MD H and Subash Kavi, S},
        title = {DEVELOPMENT AND VALIDATION OF A UV–VISIBLE SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF ORNIDAZOLE IN TABLET DOSAGE FORM},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {11},
        pages = {7243-7253},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=197097},
        abstract = {The present study was undertaken to develop and validate a simple, accurate, and economical UV–Visible spectrophotometric method for the quantitative estimation of Ornidazole in pharmaceutical tablet dosage form. Ornidazole is a nitroimidazole derivative widely used for the treatment of infections caused by anaerobic bacteria and protozoa. The analytical method was developed using methanol as the solvent system. The standard solution of Ornidazole was scanned over 200–400 nm to determine the wavelength of maximum absorption. The drug exhibited maximum absorbance at 277 nm, which was selected as the analytical wavelength for further analysis. A calibration curve was constructed in the concentration range of 2–12 µg/mL, and the method showed good linearity with a correlation coefficient of 0.999. The developed method was validated in accordance with ICH guidelines for linearity, accuracy, precision, limit of detection, limit of quantification, and robustness. The recovery values obtained during accuracy studies were within the acceptable range, indicating that the method is accurate. Precision studies showed percentage relative standard deviation values below 2%, confirming the reproducibility of the analytical procedure. The developed method was successfully applied for the estimation of Ornidazole in tablet formulation. The results demonstrated that the proposed UV spectrophotometric method is simple, reliable, and suitable for routine pharmaceutical analysis of Ornidazole in tablet dosage forms.},
        keywords = {Ornidazole, UV spectrophotometric method, ICH guidelines.},
        month = {April},
        }