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@article{199936,
        author = {Dr. Sanjeet Singh and Dr.Amitabh and Dr. Vedwati Parikh},
        title = {Hypothyroidism and Metabolic Dysregulation: Non-Pharmacological Detoxification and Regulatory Therapies},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {12},
        pages = {210-216},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=199936},
        abstract = {Hypothyroidism is a prevalent endocrine disorder characterized by reduced thyroid hormone production, leading to widespread metabolic dysregulation, including weight gain, dyslipidemia, fatigue, and impaired glucose metabolism. Conventional management primarily relies on lifelong hormone replacement therapy, which, although effective in symptom control, does not adequately address underlying metabolic dysfunction or systemic imbalances. This has prompted increasing interest in complementary and non-pharmacological therapeutic strategies.From an integrative perspective, hypothyroidism can be understood as a state of impaired metabolic regulation associated with diminished bio-transformative capacity and accumulation of metabolic toxins. Panchakarma, the classical Ayurvedic detoxification and bio-purification therapy, offers a structured approach to eliminate endogenous toxins and restore physiological balance. Procedures such as Vamana, Virechana, Basti, and Nasya are believed to modulate systemic metabolism, improve digestive and cellular function, and regulate neuro-endocrine pathways.Emerging evidence suggests that these interventions may influence thyroid function indirectly through enhancement of metabolic efficiency, reduction of inflammatory mediators, correction of gut microbiota, and improvement in insulin sensitivity. Additionally, supportive lifestyle modifications, including dietary regulation, daily regimen, and mind-body practices such as yoga and pranayama, play a crucial role in sustaining therapeutic outcomes.This article explores the role of non-pharmacological detoxification and regulatory therapies in the management of hypothyroidism and associated metabolic disturbances, highlighting the potential of Panchakarma as a holistic and integrative approach. Further scientific validation through well-designed clinical trials is warranted to substantiate its efficacy and mechanisms.},
        keywords = {Hypothyroidism, Metabolic Dysregulation, Panchakarma, Detoxification Therapy, Non-Pharmacological Treatment, Thyroid Function, Integrative Medicine},
        month = {May},
        }