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@article{201586,
        author = {Dr. Manisha Dattatray Lokhande and Dr. Dhairyasheel Yadav and Dr. Seeam P. Daf},
        title = {Mapping Ajna Chakra: A Review of Its Probable Neuroanatomical and Endocrine Connections},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {12},
        pages = {5404-5410},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=201586},
        abstract = {Ajna Chakra, traditionally described in yogic literature as the “command center” of consciousness, is considered one of the most significant psychic centers within the subtle body system. Located between the eyebrows and associated with intuition, perception, cognition, and mental clarity, Ajna Chakra occupies a central role in meditation and higher mental functioning. Ancient yogic and Ayurvedic texts describe it as the seat of wisdom, mental discipline, and internal awareness. In modern scientific interpretation, researchers have attempted to correlate Ajna Chakra with neuroanatomical and endocrine structures such as the pineal gland, pituitary gland, hypothalamus, limbic system, optic chiasma, and frontal cortical networks.
The present review explores the probable anatomical, neurological, and endocrine correlates of Ajna Chakra through an integrative analysis of classical yogic descriptions and modern biomedical sciences. The review further examines the physiological significance of meditation, pranayama, and yogic practices in modulating stress, neuroendocrine function, circadian rhythm, emotional regulation, and cognitive processes. Special emphasis is placed on the pineal gland due to its central role in melatonin secretion and consciousness regulation, which parallels many symbolic descriptions of Ajna Chakra. The article also discusses the role of Ajna Chakra imbalance in stress-related disorders, psychosomatic illnesses, anxiety, sleep disturbances, and impaired cognitive functioning. Existing experimental and clinical evidence regarding meditation-induced neuroplasticity and hormonal modulation are reviewed to establish possible scientific explanations for yogic concepts. The integration of Ayurveda, yoga, neuroscience, endocrinology, and psychophysiology provides a broader understanding of Ajna Chakra and its potential relevance in holistic health sciences.},
        keywords = {Ajna Chakra, Pineal gland, Pituitary gland, Neuroanatomy, Endocrinology, Yoga, Meditation, Ayurveda, Stress, Neurophysiology},
        month = {May},
        }