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@article{204937,
        author = {Dr  Pankaj Bablani and Manju Sharma and Siddharth Pandey and Neeraj Kumar},
        title = {Human Stem Cells: From Harvesting to Clinical Use},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {13},
        number = {1},
        pages = {4485-4496},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=204937},
        abstract = {Human stem cells possess two defining biological properties — self-renewal and differentiation — that underpin their transformative role in regenerative medicine. This article reviews the biology, classification, and harvesting of human stem cells, with emphasis on mesenchymal stem cells (MSCs), hematopoietic stem cells (HSCs), neural stem cells, and induced pluripotent stem cells (iPSCs). We describe the major harvesting methodologies — bone marrow aspiration, adipose tissue liposuction, umbilical cord collection, and peripheral blood apheresis — and outline the laboratory processes required for culture and expansion. The molecular mechanisms by which stem cells contribute to tissue healing (cell replacement, paracrine growth factor secretion, and immunomodulation) are discussed, followed by a survey of established and emerging clinical applications spanning skin grafting, bone marrow transplantation, spinal cord injury, cardiac repair, and organ regeneration. Ethical, regulatory, and safety considerations are addressed, and future directions including 3D bioprinting, organoid engineering, and gene-edited personalized medicine are highlighted.},
        keywords = {stem cells, mesenchymal stem cells, hematopoietic stem cells, iPSCs, regenerative medicine, tissue engineering, bone marrow transplantation, wound healing},
        month = {June},
        }