Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
@article{207013,
author = {P Naga Haritha and Amgoth Nandini and Burgula Sravani},
title = {Pharmaceutical Oral Films: Advances in Formulation Strategies, Manufacturing Technologies, Evaluation, Therapeutic Applications, and Future Perspectives},
journal = {International Journal of Innovative Research in Technology},
year = {2026},
volume = {13},
number = {2},
pages = {3749-3767},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=207013},
abstract = {Pharmaceutical oral films (POFs) have emerged as an advanced patient-centric drug delivery platform with multiple advantages over traditional solid oral dosage forms such as rapid disintegration, ease of administration, increased patient compliance, and the potential to enhance bioavailability through transmucosal absorption. Their applicability for juvenile, geriatric and dysphagic patients has drawn great attention in pharmacological research as well as in clinical practice. The present study highlights a detailed discussion on categorization, formulation components, production procedures, physicochemical and mechanical assessment criteria and therapeutic uses of pharmaceutical oral films. The emphasis is on the most widely used film-forming polymers, plasticizers, taste-masking techniques, and innovative production techniques such as solvent casting, hot-melt extrusion, electrospinning, and three-dimensional (3D) printing. It also features recent advances in nanotechnology, customized medicine and intelligent manufacturing technologies. Moreover, present limitations such as low drug loading capacity, moisture sensitivity, difficulty in scale-up and regulatory issues are critically explored, along with the future research prospects. The continuous improvement in materials science, pharmaceutical engineering and precision medicine is projected to considerably enlarge the therapeutic use of pharmaceutical oral films and make them a versatile and promising platform for future generation drug delivery systems.},
keywords = {},
month = {July},
}
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