Crystal Structure of 6-(4-bromophenyl)-2-((6-methylbenzofuran-3-yl) methyl) imidazo [2, 1-b] [1, 3, 4] thiadiazole  (C20H14BrN3OS)

Crystal Structure of 6-(4-bromophenyl)-2-((6-methylbenzofuran-3-yl) methyl) imidazo [2, 1-b] [1, 3, 4] thiadiazole (C20H14BrN3OS)
Author(s):
Dr. Ramakrishna Gowda
Keywords:
bromophenyl, methylbenzofuran, thiadiazole crystal x-ray study, Molecular Packing and hydrogen bonding
Abstract
There are number of reports in the literature on the synthesis and biological activities of the condensed imidazo thiazoles, appeared particularly after the discovery of novel broad spectrum anthelmintic Tetramisole With the hope of evolving a promising drug related to tetramisole, and to prepare various other biologically important compounds, the trend has been shifted to explore the drugs containing bioisosteric thiadiazoles ring in place of thiazole ring of tetramisole. Imides thiadiazole nucleus is known for diverse biological properties through innumerable derivatives since the present work involves the synthesis of thiadiazoles, imidazothiadiazole and their derivatives, we have presented a few reports on thiadiazoles and imidazothiadiazole derivatives of biological interest In the light of above observations following imidazo thiadiazol possessing chloro/bromo substituents have been subjected to X-ray diffraction studies.
Article Details
Unique Paper ID: 153791 Publication Volume & Issue: Volume 8, Issue 9 Page(s): 31 - 34
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