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Burden of MDR Acinetobacter in a tertiary care hospital

  • Unique Paper ID: 168279
  • Volume: 11
  • Issue: 5
  • PageNo: 324-328
  • Abstract:
  • Acinetobacter is a significant nosocomial pathogen that is multidrug resistant (MDR), associated with hospital infections globally, and has evolved resistance to most antibiotics by creating a variety of acquired -lactamases (1), (3). This study examined the prevalence of MDR Acinetobacter and its effects in tertiary care hospital patients in south India. Clinical samples including BAL, ET exudates, urine, blood, and other bodily fluids were collected and processed over the course of eight months in accordance with the prescribed protocol. According to CLSI recommendations, the VITEK-2 system performed the identification and AST(5-7). MDR Acinetobacter was defined as organisms resistant to any one medication in three categories of antimicrobials(8). During the study period, 19,602 samples were obtained for culture and sensitivity testing, of which 357 (1.82%) were Acinetobacter isolates, of which 98 (27.45%) were MDR isolates. The majority of MDR Acinetobacter infections came from respiratory tract samples, including ICU patients older than 60 years. The majority of these MDR isolates were intermediately resistant to colistin and all first-line antibiotics(7)(8). We can therefore draw the conclusion that there are few alternatives for treating these infections with antibiotics like polymyxin B and colistin sulfate and that the highly resistant Acinetobacter MDR strains cause a high rate of morbidity and mortality. We can use infection control procedures to stop the spread of related organisms within the hospital by detecting the MDR pathogens.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 5
  • PageNo: 324-328

Burden of MDR Acinetobacter in a tertiary care hospital

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