OXCARBAZEPINE INDUCED HYPONATREMIA: A CASE REPORT

  • Unique Paper ID: 157252
  • Volume: 9
  • Issue: 6
  • PageNo: 365-367
  • Abstract:
  • Oxcarbazepine is a well-known and effective anti-convulsant used for patients with underlying seizure disorder. It is a structural analog of carbamazepine, it follows a different metabolic pathway in which it is converted to a different active metabolite. Side effects associated with this medication are vast, in this report we will look in on the renal adverse effects, Syndrome of inappropriate anti-diuretic hormone secretion (SiADH). SiADH is a condition in which the body is making too much anti-diuretic hormone which results in too much water absorption and cause hyponatremia with neurologic sequelae. Here is a 67-year-old female patient with complaint of increased talk, insomnia for 3 months. On admission in hospital under psychiatry the patient was treated with T.Zenoxa (Oxcarbazepine) 450mg 1-0-1 and on following days patient Na decreased 135, 130, 124 mEq/L which indicated to be hyponatremic secondary to having SiADH.

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Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{157252,
        author = {ASHIMA BASHEER and RITTU R.L and DR.DHANYA DHARMAN and Dr.Shaiju S Dharan},
        title = {OXCARBAZEPINE INDUCED HYPONATREMIA: A CASE REPORT},
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {9},
        number = {6},
        pages = {365-367},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=157252},
        abstract = {Oxcarbazepine is a well-known and effective anti-convulsant used for patients with underlying seizure disorder. It is a structural analog of carbamazepine, it follows a different metabolic pathway in which it is converted to a different active metabolite. Side effects associated with this medication are vast, in this report we will look in on the renal adverse effects, Syndrome of inappropriate anti-diuretic hormone secretion (SiADH). SiADH is a condition in which the body is making too much anti-diuretic hormone which results in too much water absorption and cause hyponatremia with neurologic sequelae. Here is a 67-year-old female patient with complaint of increased talk, insomnia for 3 months. On admission in hospital under psychiatry the patient was treated with T.Zenoxa (Oxcarbazepine) 450mg 1-0-1 and on following days patient Na decreased 135, 130, 124 mEq/L which indicated to be hyponatremic secondary to having SiADH.},
        keywords = {Hyponatremia, SiADH, Adverse effects, Anti-convulsant},
        month = {},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 9
  • Issue: 6
  • PageNo: 365-367

OXCARBAZEPINE INDUCED HYPONATREMIA: A CASE REPORT

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