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@article{167263,
        author = {Karnati Jeevitha and N.Naveen Kumar},
        title = {Optimized Ensemble Models for Predicting Diseases from Metagenomic Data},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {3},
        pages = {702-707},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=167263},
        abstract = {This study introduces an innovative ensemble deep learning approach, EnsDeepDP, for disease prediction using human metagenomics data. The method employs a combination of unsupervised and supervised learning techniques to effectively handle the high-dimensional features and limited sample sizes inherent in microbiome data. Various deep learning architectures including Convolutional Neural Networks (CNN), Long Short-Term Memory (LSTM), CNN-LSTM, and CNN-GRU are utilized alongside traditional machine learning models such as Multilayer Perceptron (MLP), Random Forest, Bagging Classifier with Random Forest, and a Voting Classifier combining Bagging Classifier with Random Forest and Decision Trees. Through extensive experimentation on six public datasets, our framework consistently outperforms existing algorithms in disease prediction tasks. Notably, the ensemble approach incorporating Bagging Classifier and Voting Classifier achieves superior performance, surpassing the 90% accuracy threshold. This comprehensive ensemble strategy showcases promising potential for advancing disease prediction accuracy in human microbiome studies.},
        keywords = {Human microbiome, ensemble deep learning, disease prediction, scoring strategy, metagenomics.},
        month = {August},
        }