Phytochemistry and Pharmacology of Coccinia grandis Linn

  • Unique Paper ID: 167562
  • Volume: 11
  • Issue: 3
  • PageNo: 1740-1743
  • Abstract:
  • The ethanolic extract of Coccinia grandis Linn. (Family: Cucurbitaceae) underwent phytochemical screening, which revealed the presence of alkaloids, reducing sugars, and saponins. The pharmacological interest in these compounds, along with the traditional medicinal use of this plant, motivated further investigation into its potential antimicrobial, antidiarrhoeal, and analgesic activities. The ethanolic extract of Coccinia grandis Linn. was tested for its pharmacological properties. At a dose of 500 mg/kg, the extract exhibited significant analgesic activity, providing 60% protection against pain (p<0.001), compared to 76% protection by the standard drug diclofenac at a dose of 50 mg/kg body weight. However, the extract showed no antidiarrhoeal activity at the same dose. These results support the traditional medicinal use of Coccinia grandis and indicate its potential for further investigation.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{167562,
        author = {Dr. Kavita Rupesh Mane and Dr. Rajendra Patil and Prof. Swati Burungale},
        title = {Phytochemistry and Pharmacology of Coccinia grandis Linn},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {3},
        pages = {1740-1743},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=167562},
        abstract = {The ethanolic extract of Coccinia grandis Linn. (Family: Cucurbitaceae) underwent phytochemical screening, which revealed the presence of alkaloids, reducing sugars, and saponins. The pharmacological interest in these compounds, along with the traditional medicinal use of this plant, motivated further investigation into its potential antimicrobial, antidiarrhoeal, and analgesic activities. The ethanolic extract of Coccinia grandis Linn. was tested for its pharmacological properties. At a dose of 500 mg/kg, the extract exhibited significant analgesic activity, providing 60% protection against pain (p<0.001), compared to 76% protection by the standard drug diclofenac at a dose of 50 mg/kg body weight. However, the extract showed no antidiarrhoeal activity at the same dose. These results support the traditional medicinal use of Coccinia grandis and indicate its potential for further investigation.},
        keywords = {Phytochemistry, Antipyretic activity, Antidirroheal activity, Pharmacology},
        month = {September},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 3
  • PageNo: 1740-1743

Phytochemistry and Pharmacology of Coccinia grandis Linn

Related Articles