Phytochemistry and Pharmacology of Coccinia grandis Linn

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Dr. Kavita Rupesh Mane; Dr. Rajendra Patil; Prof. Swati Burungale

Phytochemistry and Pharmacology of Coccinia grandis Linn

Authors: Dr. Kavita Rupesh Mane, Dr. Rajendra Patil, Prof. Swati Burungale

Unique Paper ID: 167562
Volume: 11
Issue: 3
PageNo: 1740-1743

Keywords: Phytochemistry Antipyretic activity Antidirroheal activity Pharmacology

Abstract:
The ethanolic extract of Coccinia grandis Linn. (Family: Cucurbitaceae) underwent phytochemical screening, which revealed the presence of alkaloids, reducing sugars, and saponins. The pharmacological interest in these compounds, along with the traditional medicinal use of this plant, motivated further investigation into its potential antimicrobial, antidiarrhoeal, and analgesic activities. The ethanolic extract of Coccinia grandis Linn. was tested for its pharmacological properties. At a dose of 500 mg/kg, the extract exhibited significant analgesic activity, providing 60% protection against pain (p<0.001), compared to 76% protection by the standard drug diclofenac at a dose of 50 mg/kg body weight. However, the extract showed no antidiarrhoeal activity at the same dose. These results support the traditional medicinal use of Coccinia grandis and indicate its potential for further investigation.

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Cite This Article

ISSN: 2349-6002
Volume: 11
Issue: 3
PageNo: 1740-1743

Phytochemistry and Pharmacology of Coccinia grandis Linn

Available:https://ijirt.org/article?manuscript=167562

Impact Factor
8.01 (Year 2024)

UGC Approved
Journal no 47859

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