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@article{169416,
        author = {P Varalakashmi and Vishal CS and Saleh Nasir and Lavkush and Sayan Chaterjee and E Sateesh Kumar and Padma L and Sapna Patil},
        title = {A STUDY ON PRESCRIBING PATTERN OF ANTIBIOTICS IN GASTROENTEROLOGY DEPARTMENT OF A TERTIARY CARE HOSPITAL.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {6},
        pages = {1451-1459},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=169416},
        abstract = {BACKGROUND: This study investigates antibiotic prescribing patterns within the Gastroenterology department of a tertiary care hospital to gain insights into the utilization of antibiotics in the treatment of gastrointestinal conditions, with potential implications for patient care and antimicrobial stewardship.
METHODS: A cross-sectional study was carried out among 281 inpatients in a tertiary care hospital in Bangalore. 
RESULTS: Most patients fall within the 20-30 age group, with males being more prevalent. The 20-30 age group accounts for 22.06% of patients, while the 90-100 age group has the lowest representation at 0.71%. Acute gastroenteritis is the most common diagnosis, representing 30.25% of cases, followed by acute pancreatitis at 8.19%, other diagnoses including  peptic ulcer 7.83% and GERD 15.30%. Comorbidities are common, with Hypertension, Diabetes, and other conditions affecting 31.32% of patients. A substantial portion (33.10%) has no recorded comorbidities. Intravenous administration is the most preferred route, accounting for 82.49% of cases. Metronidazole is the most frequently prescribed antibiotic (31.16%). Among patients above 50 years, 63.6% are taking five or more drugs, while 36.4% are taking fewer than five drugs. Notable drug interactions include Ciprofloxacin and Metronidazole, categorized as having a "moderate" level of interaction. Adverse drug reaction(ADR)  instances are classified into Definitive, Probable, and Unlikely categories, with "Unlikely" ADRs having the highest frequency. The most common action taken in response to ADRs is "Drug Withdrawn" (63%), followed by "Dose Altered" (26%).
CONCLUSION: Analysis reveals high patient prevalence in the 20-30 age group, with a male majority, prominent diagnosis of acute gastroenteritis, and common comorbidities. Intravenous administration and metronidazole prescription dominate. Polypharmacy is significant in patients over 50, with specific drug interactions noted, primarily involving Ciprofloxacin and Metronidazole, and the main approach to adverse drug reaction management is drug withdrawal. This comprehensive analysis informs patient care and treatment strategies in the Gastroenterology department.},
        keywords = {Antibiotics, Gastroenterology, Prescribing Pattern, Who Indicators, Adverse Drug Reaction.},
        month = {November},
        }