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@article{172372,
        author = {Dr.Ashutosh Padhan and Santosh Kumar Dash and Abdul Sayeed Khan},
        title = {Phytochemical screening and anti- inflammatory    docking of Potential plant Vitex negundo},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {8},
        pages = {2966-2976},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=172372},
        abstract = {The rise in drug resistance shown by human pathogenic bacteria become a clinical crisis from all over the world. In order to control the situation, it is essential to develop alternative drugs for the treatment of infectious diseases. Recent advancements in the field of green synthesis have enabled the development of alternative drugs.  The work described in this paper details the phytochemical screening and pharmacological study of Vitex negundo leaf extracts, which is mentioned in Ayurveda as a potential medicine to cure several diseases. Identification, Collection & Authentication of plants, Drying & Storing of the plants for studies, Extraction, Qualitative Phytochemical Screening reveals the presence of phytochemical constituents like carbohydrates, alkaloids, tannins, saponins, and flavonoids. Microbiological investigation revealed that Staphylococcus aureus and E. coli was highly inhibited by methanolic extract of vitex negundo. We used molecular docking to better understand the mechanism underlying the extract's anti-inflammatory effects with   a   high   docking   score.},
        keywords = {Drug Resistance, Vitex negundo, Staphylococcus aureus, methanolic extract},
        month = {January},
        }