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@article{172350,
        author = {Ashutosh Padhan and Santosh Kumar Dash and Abdul Sayeed Khan},
        title = {FORMULATION AND EVALUATION OF FAMCICLOVIRGEL MICROEMULSIONS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {8},
        pages = {3081-3089},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=172350},
        abstract = {Microemulsions are characterized as the dispersion of at least two fluids that are not easily mixed, with the droplets being extremely minute in size (often in the range of nanometers, such as 20-200 nm). Transparent or translucent systems exhibit thermodynamic equilibrium between the components found in distinct phases. The gelling microemulsion drug delivery system is an innovative method for formulating pharmacological molecules for transdermal administration. This strategy amalgamates the benefits of both solutions, including the precision and ease of administration of the former, and the extended duration of the latter. Therefore, the gel-forming system extends the duration that the drug remains in the body and enhances the absorption of the drug through the skin. The main benefit of this formulation is the ability to deliver precise and consistent amounts with enhanced penetration. Microemulsion is a highly promising method for addressing the challenges associated with formulating hydrophobic/lipophilic medicines. Apreformulation study was conducted, which involved investigating the solubility of the medicine and studying the compatibility between the drug and excipients. The hydrogel was assessed for its viscosity, pH, in vitro drug release, spreadability, and diffusion research. The globule size of the microemulsion was assessed. Hydrogel samples from the final formulations F3&F6 were retained for a stability study lasting one month.},
        keywords = {Microemulsions, Gelling, Transdermal, Hydrogel},
        month = {January},
        }