FORMULATION & EVALUATION OF INSULIN MICROPARTICALS.

  • Unique Paper ID: 172649
  • PageNo: 805-811
  • Abstract:
  • Objective: To develop and evaluate insulin-loaded microparticles for oral delivery, enhancing bioavailability and patient compliance. This study aimed to formulate and evaluate insulin-loaded microparticles for oral delivery. Microparticles were prepared using sodium alginate, lactate dehydrogenase, and PLGA. Results showed improved insulin loading, controlled release, and stability. In vitro studies demonstrated enhanced bioavailability and safety. Methods: Insulin-loaded microparticles were formulated using sodium alginate, lactate dehydrogenase, and PLGA via a Polymerisation method. Particle size, zeta potential, insulin loading, and in vitro release were characterized.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{172649,
        author = {Sneha S. Marlpalle and Abhilasha R. Pawar and Shubhangi S. Nilkanthe and Rutuja R. Parwe},
        title = {FORMULATION & EVALUATION OF INSULIN MICROPARTICALS.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {9},
        pages = {805-811},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=172649},
        abstract = {Objective: To develop and evaluate insulin-loaded microparticles for oral delivery, enhancing bioavailability and patient compliance. This study aimed to formulate and evaluate insulin-loaded microparticles for oral delivery. Microparticles were prepared using sodium alginate, lactate dehydrogenase, and PLGA. Results showed improved insulin loading, controlled release, and stability. In vitro studies demonstrated enhanced bioavailability and safety.
Methods: Insulin-loaded microparticles were formulated using sodium alginate, lactate dehydrogenase, and PLGA via a Polymerisation method. Particle size, zeta potential, insulin loading, and in vitro release were characterized.},
        keywords = {Diabetes, Insulin, Microparticles.},
        month = {February},
        }

Cite This Article

Marlpalle, S. S., & Pawar, A. R., & Nilkanthe, S. S., & Parwe, R. R. (2025). FORMULATION & EVALUATION OF INSULIN MICROPARTICALS.. International Journal of Innovative Research in Technology (IJIRT), 11(9), 805–811.

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