Unravelling the Enigma of Alien Hand Syndrome: The Disassociation Between Intent and Action and the Psychological Turmoil of Losing Control

  • Unique Paper ID: 173496
  • PageNo: 493-503
  • Abstract:
  • Alien Hand Syndrome (AHS) is an intriguing neurological anomaly, conceptualized by the feeling of alien-ness associated with involuntary and seemingly extra-volitional limb movements that often feel extraneous or out of sync with the intent of the individuals. Being a distinct taxonomic entity, its purposeful movements usually serve as the key distinguishing feature that sets it apart from other common types of purposeless movement disorders, such as tremors, chorea, and dystonia. Disruptions in certain brain regions, such as the corpus callosum, frontal lobe, and parietal lobe, which are in charge of motor control and body awareness, are responsible for the unique presentation seen in alien hand syndrome (AHS). A comprehensive literature search was conducted across PubMed, Google Scholar, and Medscape, using broad and specific keywords related to Alien Hand Syndrome (AHS). We herein review the pathophysiology behind the disassociation between the action and intent in an individual with AHS and the psychological impact it has on the patient.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{173496,
        author = {Pavan Kumar Padarthi and Aamna Baig and Shradha Parameswaran and Murali Chand Ginjupalli},
        title = {Unravelling the Enigma of Alien Hand Syndrome: The Disassociation Between Intent and Action and the Psychological Turmoil of Losing Control},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {10},
        pages = {493-503},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=173496},
        abstract = {Alien Hand Syndrome (AHS) is an intriguing neurological anomaly, conceptualized by the feeling of alien-ness associated with involuntary and seemingly extra-volitional limb movements that often feel extraneous or out of sync with the intent of the individuals. Being a distinct taxonomic entity, its purposeful movements usually serve as the key distinguishing feature that sets it apart from other common types of purposeless movement disorders, such as tremors, chorea, and dystonia. Disruptions in certain brain regions, such as the corpus callosum, frontal lobe, and parietal lobe, which are in charge of motor control and body awareness, are responsible for the unique presentation seen in alien hand syndrome (AHS). A comprehensive literature search was conducted across PubMed, Google Scholar, and Medscape, using broad and specific keywords related to Alien Hand Syndrome (AHS). We herein review the pathophysiology behind the disassociation between the action and intent in an individual with AHS and the psychological impact it has on the patient.},
        keywords = {Alien hand syndrome},
        month = {March},
        }

Cite This Article

Padarthi, P. K., & Baig, A., & Parameswaran, S., & Ginjupalli, M. C. (2025). Unravelling the Enigma of Alien Hand Syndrome: The Disassociation Between Intent and Action and the Psychological Turmoil of Losing Control. International Journal of Innovative Research in Technology (IJIRT), 11(10), 493–503.

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