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@article{174280,
        author = {Palakurthi Jaya Sri and Dr Eshwar Goud and Dr Abhishek Patil},
        title = {Tiny Organism, Big Impact: Citrobacter Sedlakii and Neonatal Brain Abscess},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {10},
        pages = {3249-3251},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=174280},
        abstract = {Background: Citrobacter species are facultative anaerobic, Gram-negative bacilli commonly found in the environment and the human gastrointestinal tract. They are associated with severe infections such as neonatal sepsis, meningitis, and brain abscesses. Among them, Citrobacter sedlakii is an emerging but rare pathogen in neonatal infections.
Case Presentation: We report the case of a preterm neonate with C. sedlakii meningitis and brain abscess. The infant, born at 32 weeks of gestation as the first of twins to a primigravida mother, presented with fever and seizures on day five of corrected gestational age. Initial neurosonography revealed large, multiloculated cystic lesions in the cerebral parenchyma, confirmed on MRI as abscesses with mass effect. Surgical drainage was performed, and C. sedlakii was isolated from the pus culture. The organism was susceptible to tigecycline, gentamicin, levofloxacin, and colistin. The patient received intravenous tigecycline for four weeks, along with metronidazole and supportive care, leading to clinical improvement.
Conclusion: This case highlights the need for complete biochemical identification of Citrobacter isolates to assess their pathogenic potential. This is the third reported case of neonatal meningitis and brain abscess due to C. sedlakii. Early recognition and appropriate antibiotic therapy are critical in reducing morbidity and mortality in affected neonates.},
        keywords = {Citrobacter sedlakii, neonatal meningitis, brain abscess, preterm, tigecycline},
        month = {March},
        }