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@article{178285, author = {Jay Vishwakarma and Sachin Bhade and Sachin Kumar and Sachin Kumar jayswal and Sahil Siddiqie and Salakram Bairagi and Rohit Baghel and Dr. Jagdish C Rathi}, title = {Eco-Friendly TLC of Ciprofloxacin Using Mixed Hydrotropic Solvent Systems}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {11}, number = {12}, pages = {3578-3580}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=178285}, abstract = {This study explores the use of mixture of hydrotropic blends as green alternatives to organic solvents for the Thin Layer Chromatography (TLC) of ciprofloxacin, a common broad-spectrum antibiotic with low solubility profile. Sodium benzoate, Urea and sodium salicylate were employed as hydrotropes in the ratio of 1:2:1 to substitute the organic solvents as the mobile phase. The Rf values obtained were compared across the different systems, the Rf value for organic and hydrotropic blends were 0.61 ± 0.02 and 0.63 ± 0.03 respectively, highlighting the potential of hydrotropes in future chromatographic applications. This approach aligns with green chemistry principles by reducing the reliance on hazardous organic solvents.}, keywords = {Ciprofloxacin, Mixed Hydrotropy, Sodium Benzoate, Sodium Salicylate, Thin Layer Chromatography, Green Chemistry}, month = {May}, }
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