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@article{182171,
        author = {Jay Vishwakarma and Karan Singh and Anjali Gour and Sumit Kumar Gupta and Aaditya Kumar and Jagdish C. Rathi},
        title = {Hydrotropic Mobile Phases: A Sustainable and Efficient TLC Approach for Acetaminophen Analysis},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {2},
        pages = {1250-1252},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=182171},
        abstract = {The present research study introduces a novel mixed hydrotropic solvent system as an alternative green chemistry based mobile phase for the Thin Layer Chromatography (TLC) separation of acetaminophen. Traditional TLC solvents are often associated with high toxicity, volatility, and environmental burden. The study utilized sodium benzoate, thiourea and sodium salicylate in aqueous systems as effective hydrotropes for the development of a mobile phase. The hydrotropic mixture in 1:2:1 (sodium salicylate: thiourea: sodium benzoate) was compared with the conventional mobile phase and results showed comparable results, with proposed hydrotropic blend offering better environmental and cost profiles. These findings suggest a viable, sustainable, and non-toxic alternative to traditional organic solvents used in pharmaceutical analysis.},
        keywords = {Thin Layer Chromatography, Hydrotropes, Green Chemistry, Eco-friendly Solvents},
        month = {July},
        }