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@article{181020,
        author = {H. Saraswathi and Dasari Vasavi Devi and Dr. D. Swarnalatha},
        title = {STABILITY INDICATING ANALYTICALMETHOD DEVELOPMENT AND VALIDATION OF ALFUZOSIN HYDROCHLORIDE AND TADALAFIL BY USING RP-HPLC},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {1},
        pages = {3680-3688},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=181020},
        abstract = {A simple, accurate, sensitive, and repeatable reverse phase high performance liquid chromatography (RP-HPLC) method has been created to measure s amount of Tadalafil and Alfuzosin HCl in medicinal dosage form. For the chromatographic separation of Tadalafil and Alfuzosin HCl on the Waters Alliance-e2695, a Luna Phenyl Hexyl (250x 4.6mm, 5µ) column was used, and the mobile phase was made up of 30:70% v/v Acetonitrile, Ammonium acetate pH-3.0, and OPA. The flow rate was 1 ml/min, and a photodiode array detector working at room temperature was used for absorption at 294nm. In the case of Tadalafil, the number of potential plates was NLT 2000, and the tailing factor should not be more than 2. It is always less than 2.0 for the relative standard deviation of peak areas across all measures. Following ICH guidelines, the suggested method was proven to work. It was discovered that the method was easy, cheap, accurate, exact, and strong for studying the stability of Tadalafil and Alfuzosin HCl in large amounts.},
        keywords = {HPLC, Tadalafil, Alfuzosin HCl,specificity, purity and ICH guidelines. ABBREVATIONS:  HPLC-High performance liquid chromatography, HCL-Hydrochloric Acid},
        month = {June},
        }