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@article{183012, author = {Amrutha J A and Josina Joseph and Chintha Chandran and Drishya L and Shaiju S Dharan}, title = {PULMONARY PUZZLE: SCLERODERMA INDUCED CRYPTOGENIC ORGANIZING PNEUMONIA – A RARE CASE REPORT}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {12}, number = {2}, pages = {4389-4392}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=183012}, abstract = {Scleroderma, also known as systemic sclerosis, is a chronic autoimmune connective tissue disease characterised by skin thickening and organ fibrosis. Among the most serious complications are pulmonary manifestation, which can significantly affect the quality of life and prognosis. Cryptogenic Organising Pneumonia (COP) is a form of idiopathic diffuse Interstitial Lung Disease (ILD) that develops in response to a variety of unknown irritants. A 61-year-old female patient came to pulmonology department with the complaints of cough, worsening at night. The patients have no medical, social or family history. On physical examination, the patient had bilateral crepts. According to HRCT thorax, the patient was found to have cryptogenic organising pneumonia and hypersensitivity pneumonitis. In ANA profile, Scl- 70 shown to be strongly positive, which conclude systemic sclerosis and RA factor 14.9 IU/ml (<12 IU/ml). Patient was treated with IV antibiotics, corticosteroids and other supportive measures. Patient improved symptomatically and discharged with stable vitals. This case points out the connection between scleroderma and pulmonary complications, which is crucial for timely diagnosis, effective management and prevention of disease progression.}, keywords = {Scleroderma, Cryptogenic organising pneumonia, Fibrosis, Microvascular damage.}, month = {August}, }
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