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@article{184217,
        author = {Ms. Dewanjali Rathore and Anurag aman sahu and Varsha Sahu and Sakshi Singh and Rishu kumar},
        title = {Sustainable Materials and Eco-Friendly Approaches in Transdermal Patch Development: A Comprehensive Review},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {4},
        pages = {625-631},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=184217},
        abstract = {A novel drug delivery system in the form of a transdermal patch is designed to deliver therapeutic agents through the skin for a systemic effect. Transdermal patches, unlike traditional oral or injectable drugs, allow a non-invasive, controlled, and sustained release of drug. Transdermal patches have a number of advantages including improved patient compliance, reduced side effects, and bypassing the first-pass metabolism of the liver. Many medications, including hormones, analgesics, nicotine, and antihypertensive, are administered through these patches. A substrate layer, drug storage of matrix-type, a rate-controlling the membrane itself, an adhesive layer, and a protective liner constitute the basic elements of transdermal patches. Emerging technologies in transdermal delivery, such as smart patches, nanoparticles, and microneedles, have widened the scope of applications for this drug delivery method and opened the way to administer insulin, biologics, and even vaccines. Moreover, the integration of detectors and surveillance systems in transdermal pads provides new possibilities for real-time health monitoring and customized drugs. Despite these advances, challenges like medication stability, skin permeability, and the need for patient-specific formulations remain. While the future is headed in the direction of more efficacious, targeted, and adaptive therapies, transdermal patches are still a viable candidate for controlling chronic diseases and administering non-invasive therapeutics.},
        keywords = {Analgesics, Controlled release, Sustained release, Transdermal patch},
        month = {September},
        }