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@article{184731, author = {Nilesh Gupta and Kishan Kumar}, title = {Hybrid Convolutional Neural Network and Transformer-Based Deep Learning Approach for Early Lung Cancer Detection}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {12}, number = {4}, pages = {3067-3077}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=184731}, abstract = {Lung cancer continues to be among the most common cancers and a major cause of cancer-related deaths globally, thus, stress the need for early detection and accurate diagnosis. In the present paper we propose a Hybrid CNN-Transformer deep learning framework, which combines both the local spatial feature extraction strength of CNN and the ability of global contextual modeling of Transformer for CT-based automated lung cancer detection. For clinical transparency, explainable AI methods, such as Grad-CAM and attention heatmaps, were included for model interpretation. Performance was evaluated on benchmark datasets in experiments as high as 96.8% accuracy, 96.1% precision, 95.7% recall, 95.9% F1-score, and 97.3% AUC., outperforming CNN, Vision Transformer, CNN–RNN Hybrid respectively. The results demonstrate the promise of the proposed framework for computer-aided diagnostic (CAD) systems to provide clinically-meaningful, interpretable and robust decision support in early lung cancer screening.}, keywords = {Lung Cancer Detection, CNN–Transformer Hybrid, Explainable AI, Deep Learning, Medical Imaging, Computer-Aided Diagnosis.}, month = {September}, }
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