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@article{185044, author = {Indumathi K P and Suriyavathana Muthukrishnan and Thamarai Ganesan and Braivy Anto}, title = {PHYTOCHEMICAL ANALYSIS, BIOCHEMICAL PROFILE, ANTIBACTERIAL ANALYSIS OF Andrographis lineata (PERIYANANGAI) LEAVES EXTRACT}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {12}, number = {5}, pages = {1-12}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=185044}, abstract = {Nature has been a source of medicinal agents for thousands of years and since the beginning of mankind. The application of medicinal plants especially in traditional medicine is currently well acknowledged. Medicinal plants are an important source for the therapeutic remedies of various ailments. Andrographis lineata is one such plant which is extensively used in herbal medicines due to its vast and time proven medicinal properties. Andrographis lineata.Nees belongs to the Acanthaceae family. All parts of this plant are medicinally important in the traditional system of medicine in India and have been used extensively in snake bite and as an antipyretic. In Hilly regions of South India, the leaves extract is a traditional remedy for the treatment of liver disease, infectious disease, diabetes, cancer, fever-causing diseases, loss of appetite, irregular stools and diarrhea. The present study was conducted to evaluate phytochemical screenings of Andrographis lineata leaves. A. lineata leaves extract possess a wide range of phytocompounds which has been exposed by the screening with various solvents like Aqueous, Ethanol, Methanol, Acetone and Hexane. The screening showed the presence of various phytochemicals like alkaloids, flavonoids, phenols, tannins, saponins and terpenoids. The quantitative analysis exhibited high number of Alkaloids, flavonoids and phenols, and biochemical constitutents includes carbohydrate, protein, Irin, Calcium and Vitamin A, C. Thin Layer Chromatography (TLC) method done for identification phytoconstituents. Quantitative analysis indicated high alkaloid concentrations and nutritional components, while antibacterial tests showed concentration- and solvent-dependent efficacy against bacteria like B. subtilis and E. coli, potentially through mechanisms involving cell membrane disruption or enzyme inhibition.These results provide pharmacological evidence for the plant can be used as medicinal agent in folklore medicine.}, keywords = {}, month = {September}, }
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