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@article{186016,
author = {Jyoti Dinkar Bhosale and Priti V. Pancholi and Varsha B Raule and Bharat Madhavrao Pawar},
title = {Breast Cancer: Exploring Causes, Deciphering Molecular Signaling Pathways, Identifying Therapeutic Targets, and Developing Treatment Strategies},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {12},
number = {5},
pages = {3443-3451},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=186016},
abstract = {Breast cancer remains the most prevalent malignancy among women worldwide, driven by genetic, hormonal, and environmental factors. Advances in molecular biology have led to improved classification based on molecular subtypes, receptor status, and tumor characteristics, allowing for more precise diagnostic and therapeutic strategies. Traditional treatments such as surgery, chemotherapy, and radiation remain fundamental, but targeted therapies, including monoclonal antibodies and kinase inhibitors, have significantly improved patient outcomes. Despite progress, challenges like metastasis, drug resistance, and tumor heterogeneity persist. Research into molecular signaling pathways, genetic mutations, and non-coding RNAs continues to provide new therapeutic insights. Future advancements should focus on early detection, predictive biomarkers, and personalized medicine to enhance survival rates and quality of life. A multidisciplinary approach integrating genetics, immunotherapy, and advanced diagnostics is crucial for improving breast cancer treatment outcomes.},
keywords = {Breast cancer, molecular classification, genetic mutations, signaling pathways, targeted therapy, receptor status, tumor heterogeneity, personalized medicine},
month = {October},
}
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