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@article{188556,
        author = {Ms. Aditi Ankush Kuber and Mr. Arshad A Ansari and Dr. Sunil S Jaybhaye},
        title = {MYOCARDIAL INFRACTION DISEASE: TO STUDY OF PATHOLOGY},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {2913-2923},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=188556},
        abstract = {Myocardial infarction (MI), commonly known as a heart attack, is the disease of the blood vessels supplying the heart muscle (Myocardium) i.e. coronary heart disease. The area of heart muscle that has either zero flow or so little flow that it cannot sustain cardiac muscle function is said to be infracted and the overall process is called a myocardial infarction. MI are of two types; transmural and subendocardial. Mainly it is caused due to oxidative stress and atherosclerosis. Chest pain is the most common symptom of acute MI and is often described as a sensation of tightness, pressure, or squeezing. Other symptoms include diaphoresis (an excessive form of sweating), shortness of breath (dyspnea), weakness, light-headedness, nausea, vomiting, and palpitations. The most common symptoms of MI in women include dyspnea, weakness, and fatigue, sleep disturbances. It can be treated by using blockers, diuretics, ACE inhibitors, calcium channel blockers and nitrates.
The pathophysiology of MI is multifactorial, with factors such as atherosclerosis, thrombosis, and inflammation playing crucial roles. Complications of MI can include heart failure, cardiogenic shock, and arrhythmias. Diagnosis of MI involves clinical evaluation, imaging studies, and biomarker testing. Treatment of MI includes reperfusion therapy, medical management, and cardiac rehabilitation. Reperfusion therapy, including thrombolytic therapy and primary percutaneous coronary intervention, is the cornerstone of treatment for ST-segment elevation MI. Medical management involves antiplatelet and anticoagulation therapy, as well as beta-blockers, while cardiac rehabilitation can help improve cardiovascular function and reduce the risk of further cardiac events. Prompt diagnosis and appropriate treatment are essential for improving outcomes and reducing morbidity and mortality associated with MI.},
        keywords = {Myocardial Infarction; Atherosclerosis; Transmural; Subendocardial; Oxidative Stress},
        month = {December},
        }