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@article{189098,
        author = {PRATIK J.JAGTAP and PRATIK N.SHELAR and VANASHRI PARDESI},
        title = {A BRIEF REVIEW ON: RHEUMATOID ARTHRITS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {4664-4670},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=189098},
        abstract = {Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disease that primarily affects the lining of the synovial joints and is associated with progressive disability, premature death, and socioeconomic burdens. The disease is three times more common in women as in men. It affects people of all races equally. Genetic factors may play some role in RA either in terms of increasing susceptibility to developing the condition or by worsening the disease process. The main genetic marker identified with rheumatoid arthritis is HLA. Candidate genes responsible for rheumatoid arthritis are HLA-DRB1, HLA-DRB4, PTPN22, and PAD I4. Alteration of these genes results in production of inflammatory cells. The symptoms include fatigue, lack of appetite, low-grade fever, muscle and joint aches, and stiffness. Tissue inflammation may lead to pericarditis, shortness of breath followed by chest pain.
It is characterized by persistent inflammation that primarily affects the peripheral joints. It usually starts as an insidious symmetrical arthritis and has an unpredictable and variable course, although pain and disability can be minimized if the condition is recognized early and treated promptly and appropriately.},
        keywords = {},
        month = {December},
        }