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@article{190127,
        author = {Mohd Abdul Hadi and B.Satya Prasanna and B. Deekshitha and E.Swetha and K.Bhavana and M. Ankitha},
        title = {DEVELOPMENT AND IN VITRO EVALUATION OF DEXLANSOPRAZOLE CONTROLLED RELEASE TABLETS CONTAINING NATURAL POLYMERS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {4249-4254},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190127},
        abstract = {The aim of the present work is to formulate and evaluate controlled release of Dexlansoprazole matrix tablets used for treatment of gastroesophageal reflux disease (GERD). Development of CR Dexlansoprazole is proposed considering the adverse event profile and high fluctuation index of Dexlansoprazole observed with CR dosage forms. Dexlansoprazole was subjected to Preformulation studies, based on the results obtained Dexlansoprazole controlled release tablets were successfully formulated. Formulations prepared by direct compression technique. Set of trials were formulated for which Dexlansoprazole evaluated parameters (bulk density, tapped density, compressibility index, hausner’s ratio, weight, thickness, hardness) were found to lie within the specifications. Dissolution study was performed in USP type II apparatus at 100 RPM in pH 6.8 phosphate buffer. From the results of the in vitro study it appears that the release of the Dexlansoprazole was significantly influenced by the characteristics of the polymer used.},
        keywords = {Dexlansoprazole, natural polymers, FTIR studies, Direct compression technique, in vitro drug release studies.},
        month = {January},
        }