Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{190653,
        author = {Dr.Hema Manogna Narne and Prathipati Srujan Kishore and Avutapalli Mercy and Guttikonda Veda Sarvani and Settineni Venkata Naresh and Thumma Lakshmi keerthi reddy and Raj Kumar Tirupathi Reddy Macha},
        title = {A NARRATIVE REVIEW OF ANTIBIOTIC PRESCRIBING APPROPRIATENESS IN TERTIARY CARE SETTINGS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {3784-3791},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=190653},
        abstract = {Antibiotics are among the most commonly prescribed medications in tertiary care hospitals, where critically ill and complex patients often require prompt empirical therapy. However, inappropriate antibiotic use, including incorrect drug selection, dosage, duration, and route of administration, contributes significantly to antimicrobial resistance, increased healthcare costs, and adverse patient outcomes. Despite the availability of clinical guidelines and antimicrobial stewardship initiatives, irrational antibiotic prescribing remains a major global and national concern. The present study aims to evaluate the appropriateness of antibiotic use among hospitalized patients in a tertiary care hospital and to analyze prescribing patterns with respect to indication, drug choice, dose, route, and duration in comparison with standard treatment guidelines and available microbiological evidence. A prescription audit and drug utilization review were conducted among inpatients receiving antibiotic therapy, and prescriptions were assessed for rationality based on established clinical standards. The study identified frequent use of empirical and broad-spectrum antibiotics, along with gaps in guideline adherence, documentation of indications, and timely modification of therapy based on culture and sensitivity results. These findings highlight the potential risk of antimicrobial resistance, adverse drug reactions, and prolonged hospital stays. Regular prescription audits and strengthened antimicrobial stewardship programs are essential to promote rational antibiotic use, improve patient outcomes, and reduce the burden of antimicrobial resistance in tertiary care settings.},
        keywords = {Antibiotics, Prescription, Rational},
        month = {January},
        }