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@article{191967,
        author = {Hetal Jahangirpuria and Neena Bhalodiya and Chaitry Shah},
        title = {High Prevalence of Cytomegalovirus IgG Positivity Among Children with Congenital Sensorineural Hearing Loss: A Retrospective Observational Study of 273 Cases},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {8},
        pages = {8150-8155},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=191967},
        abstract = {Cytomegalovirus (CMV) is a major non-genetic cause of congenital sensorineural hearing loss (SNHL), yet routine screening remains limited in many regions, including India. This retrospective observational study analyzed 273 children with congenital SNHL evaluated at a tertiary ENT center in Gujarat as a part of pre-operative evaluation for cochlear implant surgery. Demographic data, audiological profiles, and CMV IgG/IgM serology results were reviewed. CMV IgG positivity was observed in 237 children (86.8%), suggesting significant early-life CMV exposure in this population. Most CMV-seropositive children presented with severe-to-profound hearing loss, while no significant association was noted with laterality. The high seroprevalence highlights the likelihood of unrecognized congenital CMV infections, limited awareness, and absence of standardized newborn CMV screening protocols in India. These findings underscore the importance of integrating CMV-related diagnostic pathways into pediatric hearing-loss evaluations to enable timely identification and early intervention.},
        keywords = {},
        month = {January},
        }