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@article{195559,
        author = {Dr Kiran balbhim khandekar and Dr Shruthi bhokare and Dr Hauserao Patil},
        title = {MANJISHTHA IN TOXICOLOGICAL DISORDERS: CLASSICAL REFERENCES AND MODERN EVIDENCE},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {11},
        pages = {406-409},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=195559},
        abstract = {Manjishtha (Rubia cordifolia) is one of the important medicinal herbs described in classical Ayurvedic literature for its Raktashodhaka (blood purifying), Vishaghna (anti-toxic), and Varnya properties. Toxicological disorders in Ayurveda are broadly described under the concept of Visha, which includes poisoning due to animal toxins, plant toxins, artificial poisons, and environmental contaminants. Classical Ayurvedic texts such as Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya highlight the therapeutic role of Manjishtha in disorders associated with vitiation of Rakta and toxic accumulation in the body. Owing to its Tikta-Kashaya Rasa, Ushna Virya, and Katu Vipaka, the drug is believed to pacify Pitta and Kapha, purify blood, and facilitate detoxification through improved metabolic and circulatory functions. In the context of toxicological disorders, Manjishtha is traditionally indicated in conditions such as Visha, Raktadushti, skin disorders, and inflammatory conditions where toxin accumulation plays a key role in pathogenesis. Modern pharmacological studies have provided scientific support to these classical claims. Research indicates that the phytoconstituents of Rubia cordifolia, including anthraquinones, glycosides, and flavonoids, exhibit significant antioxidant, anti-inflammatory, hepatoprotective, and detoxifying activities. Experimental studies also suggest its potential role in reducing oxidative stress, enhancing hepatic detoxification mechanisms, and protecting tissues against toxin-induced damage. Thus, an integrative understanding of classical Ayurvedic references and modern scientific evidence highlights the therapeutic relevance of Manjishtha in managing toxicological conditions. The herb demonstrates promising potential as a natural detoxifying agent and supportive therapy in toxin-related disorders, warranting further clinical research and evidence-based validation in the field of integrative toxicology.},
        keywords = {Manjishtha (Rubia cordifolia); Ayurvedic Toxicology (Agada Tantra); Visha (Poisoning); Raktashodhana; Detoxification; Antioxidant Activity; Hepatoprotective Effect; Phytochemicals; Integrative Medicine.},
        month = {April},
        }