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@article{196223,
        author = {Dr Ramhet Nagar and Prof Dr Pramod Kumar Mishra and Dr Bhanu Priya Choudhary},
        title = {The Efficacy of Indravaruni Churna in the Management of Sandhivata (Osteoarthritis): A Clinical Study},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {11},
        pages = {2414-2418},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=196223},
        abstract = {Background: Sandhivata (Osteoarthritis) is a prevalent degenerative joint disorder characterized by pain, stiffness, and inflammation. Indravaruni (Citrullus colocynthis) is a classical Ayurvedic herb renowned for its anti-inflammatory, analgesic, and Vata-Kapha pacifying properties.
Aim: To evaluate the clinical efficacy of Indravaruni  Churna, a compound herbal formulation, in patients diagnosed with Sandhivata.
Materials and Methods: A clinical study was conducted on 40 patients. Patients were administered Indravaruni Churna. Assessment was based on clinical parameters, biochemical markers, and radiological findings pre- and post-treatment. Statistical analysis was performed using paired t-tests and Wilcoxon signed-rank tests.
Results: The intervention resulted in statistically significant (p<0.0001) improvements across all clinical parameters, with pain relief of 57.96%, swelling reduction of 60.71%, and stiffness reduction of 64.13%. Biochemically, a 45.13% reduction in CRP (p<0.0001) was observed. Remarkably, 100% of patients seroconverted from RA Factor positive to negative. Radiological assessment showed a clear shift towards less severe Kellgren-Lawrence grades.
Conclusion: Indravaruni Churna demonstrated profound anti-inflammatory, analgesic, and immunomodulatory effects, providing significant clinical, biochemical, and radiological improvement in Sandhivata.},
        keywords = {Indravaruni, Citrullus colocynthis, Sandhivata, Osteoarthritis, Indrvaruni Churna, Anti-inflammatory.},
        month = {April},
        }